Sethi Lab - Gastrointestinal Cancer Research
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Pratyusha Bala, Ph.D.
Postdoctoral Fellow (2021-)

Background: I was born and raised in Southern India. My academia in science started with Bachelors in Pharmacy and Masters in Pharmacology and Toxicology. During my PhD, I subjected early-onset sporadic rectal cancer (EOSRC) samples to genomic profiling and identified novel tumorigenic mutations in known as well as previously uncharacterized genes. I reported ARID2 as a novel tumour suppressor in EOSRC and also unearthed evidence through ultra-deep RNA sequencing of EOSRC tumours indicating MAPK-signalling and Ca+ signalling pathways were differentially regulated in the absence of canonical Wnt signalling.

Research Interests/Projects: My research interest is in Cancer Genomics and Therapeutics. Starting mid-2021, I will be joining Sethi lab where I will be integrating my Genomics experience with the available mouse models and CRISPR lines to understand the clinical and functional significance of SOX9 mutations/loss in colorectal cancer. I will work with adenomas from FAP patients to understand the role of SOX9 in cell stemness and differentiation in patient organoids.
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Beyond Lab: I love baking, cooking and gardening. There was a time not so long ago when I used to love travelling and exploring things. Now a days, beyond science, my time is mostly spent on entertaining my active 2-year-old daughter.


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©2023 Sethi Lab at Dana-Farber Cancer Institute
  • HOME
  • RESEARCH
    • Cancer Genomics
    • Disease Models
    • Therapeutic Vulnerabilities
  • PEOPLE
    • Principal Investigator
    • Lab Members
    • Alumni
    • Collaborators
    • Photo Gallery >
      • Group Photos
      • Lab Events >
        • Bowling 2023
        • Thailand 2023
        • Apple picking 2022
        • Lab BBQ 2022
        • RedFox Escape Room 2022
      • Colleagues and Collaborators
  • PUBLICATIONS
  • SUPPORT
    • Jimmy Fund 2020
    • Jimmy Fund 2021
  • CONTACT